METHYLATION ACROSS THE CENTRAL DOGMA IN HEALTH AND DISEASES: NEW THERAPEUTIC STRATEGIES



The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells

Abstract YAP and TAZ, the Hippo pathway terminal transcriptional activators, are frequently upregulated in cancers.In tumor cells, they have been mainly associated with increased tumorigenesis controlling different aspects from cell cycle regulation, stemness, or resistance to chemotherapies.In fewer cases, they have also been shown to oppose cance

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Porous block mulch:

water evaporaiion losses from the soil surface constitute one of the inevitable inefficiencies of irrigation.Many types of soil coverings or mulches have been investigated for reducing evaporation losses.Studies have shown that a porous mulch can be made by cementing pea gravel with a small amount of fine sand and cement mortar to hold the gravel g

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Crushing mechanism of a mobile pellet harvester

The treatment and utilization of straw is a considerably complex type of problem in agricultural production.A mobile pellet harvester integrates the mechanisms of picking, drying, crushing, and pelletizing, thereby solving the problem caused by the traditional method and reducing human effort and material resources.The crushing mechanism of a mobil

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